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The Role of Spirituality in Mental Health

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A Brief Guide to the Biopsychosocial-Spiritual Model

We have known for a long time that good mental health is connected to biological, social, and psychological factors. Many people have also known intuitively that spiritual influences also often play a role in mental health. There is growing evidence that spirituality, often understood as meaning, purpose, transcendence, being part of something greater than self, and for some, religion, seems to mitigate against multiple mental health symptoms such as depression, suicidality, and anxiety. Those who practice spirituality also appear to live their lives with more hope and positivity and the concept of a spirit or soul as something beyond mind and body resonates with many people.


1. Expanding the Model of Mental Health

Traditional frameworks emphasize:

Increasingly, research and clinical practice support inclusion of a fourth domain:

This expanded framework is often referred to as the biopsychosocial-spiritual model.


2. What Do We Mean by “Spiritual”?

In clinical research, spirituality typically refers to:

Spirituality may also be religious — but does not have to be.


3. Major Organizations Recognizing Spiritual Dimensions

World Health Organization

The WHO’s quality-of-life instruments include spiritual well-being as a domain of health.

Substance Abuse and Mental Health Services Administration (SAMHSA)

SAMHSA’s recovery model includes:

“Purpose” and “community” frequently include spiritual dimensions.


4. Evidence Base: Key Findings

Depression & Anxiety

Research consistently shows:

Research summarized by Harold G. Koenig demonstrates associations between spiritual engagement and improved mental health outcomes.


Meaning & Existential Resilience

Viktor Frankl, in Man’s Search for Meaning, proposed that meaning is central to psychological survival.

Modern studies support:


Positive Psychology

Martin Seligman includes “Meaning” in the PERMA model[1] of flourishing. Meaning involves contributing to something beyond the self.


Neurobiological Correlates

Studies (e.g., work by Andrew Newberg) show that:


5. Clinical Implications

When Spirituality May Be Protective

When Spiritual Frameworks May Contribute to Distress


6. Exploring Spirituality

You might ask:

See Appendix 1 for an extended list of questions.


8. Conceptual Summary

Mental health is increasingly understood as involving:

Interestingly, it appears that spirituality may support better mental health and also be protective against influences that compromise mental health.

Appendix 1 – Questions for Exploring Spirituality

Spiritual well-being is not always required for mental health — but for many clients, it plays a significant protective role.

Here are some questions worth sitting with:

About meaning and purpose

About connection

About belief

About values and the inner life

About growth and doubt

The most productive spiritual questions tend to be ones you can’t quickly answer — ones that stay open and keep inviting you back. The discomfort of not knowing is often where the real exploration begins.


[1] The PERMA model is a framework for understanding well-being, developed by psychologist Martin Seligman. It consists of five core elements: Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment, which together contribute to a fulfilling and happy life. (Wikipedia)

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